Reproducible Cohort Connectomics Capstone

Formulate a narrowly scoped connectomics question answerable with FlyWire data.

Select a small neuron cohort and record its identifiers, materialization version, selection criteria, and annotation provenance.

Validate the cohort's annotations and reconstructed morphology, documenting exclusions or unresolved cases.

Build a directed cohort-connectivity table containing synapse counts and in-degree and out-degree summaries.

Create a visualization that communicates the cohort’s strongest connections.

Evaluate which findings could change because of reconstruction uncertainty, annotation ambiguity, cohort selection, or data-version changes.

Package the capstone notebook, provenance information, findings, and limitations as a reproducible project.